CSF samples collected 1 day after hUCB-MSC injections showed reduced levels of total tau, phosphorylated tau, and Aβ42. However, levels increased 4 weeks after transplantation, indicating a short duration of therapeutic effects from hUCB-MSCs. Expression levels of Galactin-3, sICAM-1, progranulin, and GDF-15 increased initially but dropped significantly within 4 weeks.
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